CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 980 enrolled
Drug / intervention
Metered Dose Inhaler +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02777125
NCT02777125N/ACompleted
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A Randomized Trial Comparing Metered Dose Inhalers and Breath Actuated Nebulizers

Le Bonheur Children's Hospital·interventional·Posted May 19, 2016·Updated Aug 15, 2017

In Brief

A clinical study evaluating Metered Dose Inhaler and Breath Actuated Nebulizer for Asthma. Completed, enrolled 980 participants.

Detailed Summary

This study is determines if metered dose inhalers are as effective as breath actuated nebulizers for the treatment of mild to moderate asthma exacerbations in pediatric patients presenting to the emergency department. Half of the participating patients received albuterol via the metered dose inhaler whereas the other half received albuterol via the breath actuated nebulizer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAsthma
Countries--
CollaboratorsUniversity of Tennessee

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedMay 19, 2016
Enrollment StartOct 1, 2014
Primary CompletionApr 1, 2015
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 10.1 years ago

Interventions

Metered Dose Inhalerdevice

A metered dose inhaler (MDI) is a small hand held pressurized canister device that contains both a medication, in this case albuterol, and a propellant. Pressing the device delivers 90mcg of albuterol. The MDI is attached to a spacer device, which is a one way holding chamber which allows the medication to be delivered over a series of breaths.

Breath Actuated Nebulizerdevice

The breath actuated nebulizer (BAN) device is a device that converts liquid medication, in this case albuterol, into an aerosol. It consists of a mouthpiece, a medication reservoir, and connective tubing that attaches to a compressor. This BAN device delivers medication when the patient takes a breath, but it can be attached to a mask and set to continuous nebulization for patients that are not able to coordinate their breaths.