At a glance
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A Phase I Study to Evaluate the Pharmacokinetic and Safety Profile of AZD9496 Following Single Dose Administration of Different Forms and Formulations in Healthy Subjects
In Brief
A Phase 1 clinical trial evaluating AZD9496 (Reference), AZD9496 Variant A, and 3 other interventions for Breast Cancer. Completed, enrolled 14 participants across 1 site.
Detailed Summary
This is a phase 1 open label single centre study of AZD9496 administered orally in healthy volunteers. The study design involves single administration of different forms, formulations and doses of AZD9496. The study is designed to investigate these different AZD9496 variants. The study will evaluate the pharmacokinetic profiles and the safety and tolerability of the different forms, formulations and doses of AZD9496 This is a fixed sequence study with 5-sequential treatment periods in healthy volunteers. Each volunteer will receive 5 single doses of AZD9496 in different forms, formulations and doses.
Study Details
Timeline
Interventions
AZD9496 (Reference)
AZD9496 Variant A.
AZD9496 Variant B
AZD9496 Variant C
AZD9496 Variant D