CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 45 enrolled
Drug / intervention
Inulin+SS +2 moredrug
Likely dose
Inulin+SS 1gfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02794766
NCT02794766Phase 2Completed
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Inulin and Streptococcus Salivarius Reduce Halitosis Associated With Tongue Coating: A Randomized Clinical Trial

Universidade de Passo Fundo·interventional·Posted Jun 9, 2016·Updated Aug 19, 2020

In Brief

A Phase 2 clinical trial evaluating Inulin+SS, S salivarius, and 1 other intervention for Halitosis and Tongue Diseases. Completed, enrolled 45 participants.

Detailed Summary

Halitosis associated with tongue coating results from the production of volatile sulfur compounds by bacterial action. The use of prebiotics and probiotics might be useful in treating such condition. The aim of this study was to evaluate the effect of the prebiotic inulin combined with the probiotic Streptococcus salivarius (SS) on halitosis by coating.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHalitosis, Tongue Diseases
Countries--
CollaboratorsCoordenação de Aperfeiçoamento de Pessoal de Nível Superior.

Timeline

Phase 2CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJun 9, 2016
Enrollment StartMar 1, 2014
Primary CompletionMay 1, 2015
Study CompletionNov 1, 2015
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 10.1 years ago

Interventions

Inulin+SSdrug

Experimental treatment: A gum of inulin 1g plus Streptococcus salivarius 1 billion CFU per oral each 12 hours for 10 days

S salivariusdrug

Active comparator: A gum of Streptococcus salivarius 1 billion CFU per oral each 12 hours for 10 days

Placebodrug

Placebo 1 gum each 12 hours for 10 days