CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 90 enrolled
Drug / intervention
Diltiazem Gel 2% +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02801305
NCT02801305Phase 2Completed
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Assessing and Comparing the Effect of Diltiazem Gel Versus Nitroglycerin Ointment in Healing Process of Scleroderma Digital Ulcers.

Mohammad Ali Nazarinia·interventional·Posted Jun 15, 2016·Updated Mar 6, 2017

In Brief

A Phase 2 clinical trial evaluating Diltiazem Gel 2%, Nitroglycerin Ointment 2%, and 1 other intervention for Digital Ulcer of Scleroderma. Completed, enrolled 90 participants across 1 site.

Detailed Summary

Digital ulcers are one of the most prevalent complications of scleroderma (systemic sclerosis). There can be found few surveys on effect of topical agents on healing process of the ulcers. Thus, the aim of this study is to assess and compare the effects of topical diltiazem on SSc digital ulcers versus topical nitroglycerin.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDigital Ulcer of Scleroderma
CountriesIran
CollaboratorsShiraz University of Medical Sciences

Timeline

Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedJun 15, 2016
Enrollment StartJun 1, 2016
Primary CompletionJan 1, 2017
Study CompletionMar 1, 2017
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 10.0 years ago

Interventions

Diltiazem Gel 2%drug

This a topical agent which will be applied on digital ulcers by scleroderma patients.

Nitroglycerin Ointment 2%drug

This a topical agent which will be applied on digital ulcers by scleroderma patients.

Vaselinedrug

This is used as the topical placebo agent.