CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 4,852 enrolled
Drug / intervention
Active TB case findingother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02808507
NCT02808507N/ACompleted
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Comparative Effectiveness/Implementation of TB Case Finding in Rural South Africa

Johns Hopkins Bloomberg School of Public Health·interventional·Posted Jun 21, 2016·Updated Sep 5, 2024

In Brief

A clinical study evaluating Active TB case finding for Tuberculosis. Completed, enrolled 4,852 participants across 2 sites.

Detailed Summary

The purpose of this study is to compare three strategies for finding TB cases in a rural Sub-Saharan African setting: 1) Screening all attendees of primary care clinics for TB; 2) Conducting household contact investigations of newly diagnosed TB cases; 3) Providing incentives to newly diagnosed TB cases and their contacts to promote contact screening for TB. For each intervention, investigators will measure comparative effectiveness in terms of cases identified as well as the cost-effectiveness and feasibility of implementation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTuberculosis
CountriesSouth Africa
CollaboratorsNational Institute of Allergy and Infectious Diseases (NIAID), Perinatal HIV Research Unit of the University of the Witswatersrand

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedJun 21, 2016
Enrollment StartJul 18, 2016
Primary CompletionJan 17, 2018
Study CompletionJan 30, 2020
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 10.0 years ago

Interventions

Active TB case findingother

Active TB case finding (ACF) refers to any number of strategies used to identify individuals with active TB disease, outside of passive case finding. In passive case finding, individuals with symptoms present at health centers for diagnosis. In active case finding, the health system makes an effort to identify TB cases before they present passively.