At a glance
ClinicalIndex Comparison RecordN/ACompleted· 210 enrolled
Drug / intervention
Closed Loop Control Ventilation +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
FiO2 Closed Loop Control Using the ZOLL 731 Series Ventilator
In Brief
A clinical study evaluating Closed Loop Control Ventilation and Manual Control Ventilation for Wounds and Injuries and Respiratory Failure. Completed, enrolled 210 participants across 1 site.
Detailed Summary
A randomized, multi-center trial involving critically-ill patients comparing conventional, manual control of inspired oxygen (FiO2) within a target range, with a computer-controlled, closed-loop FiO2 delivery using a continuous ventilator.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsWounds and Injuries, Respiratory Failure
CountriesUnited States
CollaboratorsUnited States Air Force
Timeline
N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedJun 2016
Enrollment StartDec 2016
Primary CompletionDec 2020
TodayJul 2026
First PostedJun 22, 2016
Enrollment StartDec 1, 2016
Primary CompletionDec 1, 2020
TodayJul 2, 2026
Enrollment to primary: 4 yearsPosted 10.0 years ago
Interventions
Closed Loop Control Ventilationdevice
Closed loop control ventilation using ZOLL 731 ventilator with physiologic closed-loop control software
Manual Control Ventilationdevice
Manual control ventilation using ZOLL 731 ventilator