CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 80 enrolled
Drug / intervention
NCPAPdevice
Likely dose
Not stated in record
Key inclusion· 9
  • ✓Born between 23 0/7 and 30 6/7 weeks gestational age
  • ✓At least 26 0/7 weeks corrected gestational age
  • ✓On NCPAP for at least 24 hours
  • ✓Stable on ≤0.3 FiO2 for at least 24 hours
Key exclusion· 5
  • ✕Hemodynamically or clinically significant patent ductus arteriosus (PDA) diagnosed clinically or echocardiographically, or with worsening respiratory status or pulmonary edema on chest x-ray
  • ✕Any significant congenital abnormality affecting a major organ system, airway, or musculoskeletal system
  • ✕Hemodynamic or respiratory instability or currently treated for suspected or proven sepsis (positive blood culture)
  • ✕Grade IV intraventricular hemorrhage

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02819050
NCT02819050N/ACompleted
CompareCT.gov

A Prospective Randomized Controlled Tiral Comparing Sprinting Versus Non-sprinting Approach to Wean Nasal Continous Positive Airway Pressure Support in Premature Infants Born at Less Than 30 Weeks Gestational Age

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center·interventional·Posted Jun 30, 2016·Updated Dec 10, 2021

In Brief

A clinical study evaluating NCPAP for Neonatal Respiratory Distress Syndrome and 2 related conditions. Completed, enrolled 80 participants.

Detailed Summary

Though Nasal Continuous Positive Airway Pressure (NCPAP) is a commonly used form of non-invasive neonatal respiratory support, the optimal method of weaning off NCPAP is not well established. In this prospective, two-center randomized control trial we hypothesize that gradually increasing time off NCPAP (sprinting) increases the success of weaning NCPAP off in infants born between 23 0/7-30 6/7 weeks of gestational age.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNeonatal Respiratory Distress Syndrome, Extremely Low Birth Weight Infant (ELBW), BronchoPulmonary Dysplasia
Countries--
CollaboratorsChildren's Hospital of Orange County

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJun 30, 2016
Enrollment StartJan 1, 2014
Primary CompletionJan 1, 2016
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 10.0 years ago

Interventions

NCPAPdevice

Nasal Continuous Positive Airway Pressure