CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 294 enrolled
Drug / intervention
SAIT101 +2 morebiological
Likely dose
SAIT101 1,000 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02819726
NCT02819726Phase 1Completed

A Randomized, Double-blind, Parallel Group, Multicenter Study to Compare the Pharmacokinetics, Pharmacodynamics, Safety, and Efficacy of SAIT101 Versus MabThera® Versus Rituxan® in Patients With Rheumatoid Arthritis (RA)

Archigen Biotech Limited·interventional·Posted Jun 30, 2016·Updated Feb 17, 2020

In Brief

A Phase 1 clinical trial evaluating SAIT101, MabThera, and 1 other intervention for Rheumatoid Arthritis. Completed, enrolled 294 participants across 75 sites in 11 countries.

Detailed Summary

A randomised, double blind, parallel group, multicentre study yo compare the pharmacokinetics, pharmacokinetics, safety and efficacy of SAIT101 versus MabThera® versus Rituxan® in patients with rheumatoid arthritis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBosnia and Herzegovina, Bulgaria, Czechia, Germany, Hungary, India, Mexico, Poland, South Korea, Spain, United States
Collaborators--

Timeline

Phase 1CompletedFinished
2017201820192020202120222023202420252026
First PostedJun 30, 2016
Enrollment StartOct 11, 2016
Primary CompletionApr 30, 2018
Study CompletionNov 7, 2018
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 10.0 years ago

Interventions

SAIT101biological

1,000 mg i.v. of SAIT101 on Day 1 and 15. 1,000 mg i.v. of SAIT101 on week 24 and 26 for eligible patients.

MabTherabiological

1,000 mg i.v. of MabThera® on Day 1 and 15. 1,000 mg i.v. of MabThera® on week 24 and 26 for eligible patients.

Rituxanbiological

1,000 mg i.v. of Rituxan® on Day 1 and 15. 1,000 mg i.v. of Rituxan® on week 24 and 26 for eligible patients.