CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 19 enrolled
Drug / intervention
TALIMOGENE LAHERPAREPVEC (TVEC) +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02819843
NCT02819843Phase 2Completed

A Phase II Randomized Trial of Intralesional Talimogene Laherparepvec (TALIMOGENE LAHERPAREPVEC) With or Without Radiotherapy for Cutaneous Melanoma, Merkel Cell Carcinoma, or Other Solid Tumors

Memorial Sloan Kettering Cancer Center·interventional·Posted Jun 30, 2016·Updated Jan 29, 2025

In Brief

A Phase 2 clinical trial evaluating TALIMOGENE LAHERPAREPVEC (TVEC) and Hypofractionated Radiotherapy for Melanoma and 2 related conditions. Completed, enrolled 19 participants across 3 sites.

Detailed Summary

The purpose of this phase II clinical study is to test the good and bad effects of T-VEC (talimogene laherparepvec) with or without hypofractionated radiotherapy on people with melanoma, Merkel cell carcinoma, or other solid tumors with skin metastasis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsAmgen

Timeline

Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedJun 30, 2016
Enrollment StartJun 21, 2016
Primary CompletionFeb 22, 2024
TodayJul 2, 2026
Enrollment to primary: 7.7 yearsPosted 10.0 years ago

Interventions

TALIMOGENE LAHERPAREPVEC (TVEC)drug

Hypofractionated Radiotherapyradiation