CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 601 enrolled
Drug / intervention
standard genetic education +4 moreother
Likely dose
Not stated in record
Key inclusion· 4
  • Registered to Step 0 screening of NCI-MATCH trial (EAY131)
  • Able to speak English and view a website (for primary intervention study)
  • For genetic counseling substudy: identified potential germline mutation on NCI-MATCH tumor profiling assay
  • For genetic counseling substudy: able to speak English and communicate by phone
Key exclusion· 0

None specified.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02823652
NCT02823652N/ACompleted

COMET - Communication and Education in Tumor Profiling: A Randomized Study of Pre-Disclosure Genetic Education v. Usual Care in Tumor Profiling for Advanced Cancer and a Pilot Study of Remote Genetic Counseling for Participants With Potential Germline Mutations Identified on Tumor Profiling

ECOG-ACRIN Cancer Research Group·interventional·Posted Jul 6, 2016·Updated Feb 28, 2024

In Brief

A clinical study evaluating standard genetic education, Genetic Counseling, and 3 other interventions for Advanced Malignant Neoplasm and Locally Advanced Malignant Neoplasm. Completed, enrolled 601 participants across 1 site.

Detailed Summary

This research trial studies how well pre-test genetic education and remote genetic counseling works in communicating tumor profiling results to patients with advanced cancer. Web-based genetic education before receiving tumor profiling results and remote genetic counseling for patients with potential germline mutations may increase genetic knowledge and reduce distress for patients with advanced cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedJul 6, 2016
Enrollment StartOct 25, 2016
Primary CompletionDec 26, 2019
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 10.0 years ago

Interventions

standard genetic educationother

Undergo usual care

Genetic Counselingother

Complete remote counseling

Genetic Testingother

Undergo germline testing

Internet-Based Interventionother

Complete on-line genetic education

Survey Administrationother

Ancillary studies