CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 36 enrolled
Drug / intervention
Patidegib +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02828111
NCT02828111Phase 2Completed

Double-Blind, Dose Escalating, Randomized, Vehicle-Controlled Proof of Concept Clinical Trial of Patidegib Gel 2%, 4%, and Vehicle Applied Once or Twice Daily to Decrease the GLI1 Biomarker in Sporadic Nodular Basal Cell Carcinomas

PellePharm, Inc.·interventional·Posted Jul 11, 2016·Updated Jan 8, 2019

In Brief

A Phase 2 clinical trial evaluating Patidegib and Vehicle gel for Basal Cell Carcinomas. Completed, enrolled 36 participants across 1 site.

Detailed Summary

This is a double-blind, dose escalating, randomized, vehicle-controlled study designed to compare the efficacy and safety of patidegib gel 2% and 4% applied once or twice daily in comparison with that of vehicle in patients with Basal Cell Carcinoma. One investigational center (metasite) in the United States will participate in this study. Approximately 36 subjects who meet the study entry criteria will be enrolled into one of four sequential cohorts. Within each cohort subjects will be randomized in a 2:1 ratio to receive active or vehicle gel.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedJul 11, 2016
Enrollment StartNov 11, 2016
Primary CompletionNov 9, 2017
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 10.0 years ago

Interventions

Patidegibdrug

Vehicle geldrug