CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 124 enrolled
Drug / intervention
moderate ovarian stimulation +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

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Search/NCT02834117
NCT02834117Phase 4Completed

Comparison of the Number of Visits and the Quality of Life Versus Natural Cycle in Stimulated Cycle Before Frozen Embryo Transfer

Dr Massin Nathalie·interventional·Posted Jul 15, 2016·Updated Feb 6, 2019

In Brief

A Phase 4 clinical trial evaluating natural cycle and moderate ovarian stimulation for Fertility. Completed, enrolled 124 participants across 1 site.

Detailed Summary

Embryo freezing is a technique used regularly to optimize the pregnancy rate in case of infertility. This method is performed in presence of supernumerary embryo(s) after fresh transfer, or after freeze all embryos in case of medical reasons. It is necessary to control that the transfer is performed when the endometrium is receptive, which is essential for embryo implantation and pregnancy. This period is defined as the "implantation window". Endometrial preparation can be achieved by hormone replacement therapy (HRT) or moderate ovarian stimulation (SO). The implantation window can also be assessed by monitoring of a natural cycle (NC). The objectives of this open randomized study is to compare the number of visits (ultrasound and blood tests) induced by the SO or NC as well as the women quality of life in both groups.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsFertility
CountriesFrance
Collaborators--

Timeline

Phase 4CompletedFinished
20162017201820192020202120222023202420252026
First PostedJul 15, 2016
Enrollment StartMay 1, 2015
Primary CompletionFeb 1, 2018
Study CompletionMar 1, 2018
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 10.0 years ago

Interventions

natural cycleother

Ovulation is not induced by drugs

moderate ovarian stimulationdrug

Ovulation is induced by recombinant follitropin alpha and recombinant choriogonadotropin