At a glance
ClinicalIndex Comparison Record- ✓Pregnant women ages 18–45 years
- ✓Gestational age 32–42 weeks
- ✓Preeclampsia requiring magnesium sulfate
- ✓BMI ≥35 kg/m²
- ✕Gestational age <32 weeks
- ✕Current dialysis treatment
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Randomized Trial of Magnesium Sulfate in Obese Preeclamptic Women
In Brief
A Phase 4 clinical trial evaluating Magnesium sulfate 4g loading dose, 1g/hr infusion and Magnesium sulfate 6g loading dose, 2g/hr infusion for Preeclampsia. Completed, enrolled 66 participants across 1 site.
Detailed Summary
The purpose of this study is to learn how medications participant will receive in the course of their delivery are metabolized (broken down by the body). The investigators hope to learn more about the way drugs are metabolized by pregnant women, and how those drugs are distributed in the blood and body compartments and cleared in the urine, and how maternal body weight affects the metabolism. With this information the investigators will be able to develop a treatment regimen considering factors in the body that affect magnesium levels so that the investigators can improve treatment of pregnant women. The goal of the study is to understand how different dosing of magnesium sulfate affects blood levels of the magnesium in larger women.