At a glance
ClinicalIndex Comparison Record- ✓Age 18 years or older
- ✓Diagnosed ischemic stroke verified by CT or MRI
- ✓Symptom onset within 5 days of admission
- ✓NIHSS score 2–19 (moderate baseline deficit)
- ✕Severe stroke (NIHSS ≥20)
- ✕Hip flexion score of 0 on Short Fugl-Meyer due to stroke weakness
- ✕Poor static sitting balance on global balance scale
- ✕Recent intravenous or intra-arterial rtPA administration
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Dietary Nitrate Supplements and Ischemic Stroke Recovery: A Pilot Study
In Brief
A Phase 2 clinical trial evaluating Beet it Beetroot juice and Beet It Placebo Beetroot juice for Stroke and 2 related conditions. Completed, enrolled 18 participants across 1 site.
Detailed Summary
This is a double-blind, randomized, placebo-controlled, pilot study. Participants will be randomized to receive either beetroot juice or a beetroot juice placebo, as a dietary supplement, for 30 days. Beetroot juice is high in nitrates, a chemical when ingested is found to increase blood flow to the brain. The purpose of this research study is to determine the safety and feasibility of using this nutritional intervention in (ischemic)stroke survivors, and prove that plasma levels of nitrate and nitrite increase as expected. Secondary outcomes includes measuring a comprehensive set of outcomes related to functional status post-stroke, including mobility, upper extremity strength, cognition, depression, and disability. Patients will also be randomized to MRI perfusion scanning in the region of the stroke to measure cerebral blood flow.
Study Details
Timeline
Interventions
Concentrated organic beetroot (98%) and lemon juice (2%); 70ml bottle
Concentrated organic beetroot (98%) and lemon juice (2%) with nitrate extracted; 70ml bottle. Beet It Placebo Beetroot juice.