CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 303 enrolled
Drug / intervention
DOT Adherence Monitoringbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02840877
NCT02840877N/ACompleted
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The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes

Boston Medical Center·interventional·Posted Jul 21, 2016·Updated Aug 27, 2024

In Brief

A clinical study evaluating DOT Adherence Monitoring for Tuberculosis and 2 related conditions. Completed, enrolled 303 participants across 1 site.

Detailed Summary

After HIV/AIDS, tuberculosis (TB) remains the second leading cause of death due to an infectious disease globally. Retrospective studies from many countries, including the United States and South Africa, have consistently reported that in addition to having a higher burden of TB disease, patients with problem alcohol use have worse TB treatment outcomes. This prospective study will attempt to clarify both behavioral and biologic causal mechanisms underlying the deleterious effects of problem alcohol use on TB treatment response.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTuberculosis, Alcohol Consumption, Treatment Adverse Effect
CountriesSouth Africa
CollaboratorsMedical Research Council, South Africa, Boston University, University of Cape Town, National Institute of Allergy and Infectious Diseases (NIAID), University of Stellenbosch

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedJul 21, 2016
Enrollment StartMay 16, 2017
Primary CompletionJun 28, 2022
Study CompletionOct 12, 2023
TodayJul 2, 2026
Enrollment to primary: 5.1 yearsPosted 9.9 years ago

Interventions

DOT Adherence Monitoringbehavioral

Study participants will meet with a study-employed DOT worker daily during weekdays throughout the course of their TB treatment