At a glance
ClinicalIndex Comparison Record- ✓Diagnosed with Parkinson's disease with freezing of gait
- ✓Able to walk independently without walking devices
- ✕Pre-existing or active major neurological diseases other than PD
- ✕Prior history of seizures
- ✕Implanted metallic objects that would contraindicate rTMS
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effect of Simultaneous Dual Stimulation on Freezing of Gait in Parkinson's Disease
In Brief
A clinical study evaluating rTMS and tDCS and rTMS for Parkinson Disease. Completed, enrolled 32 participants.
Detailed Summary
The purpose of this study is to investigate the effect of dual-mode non-invasive brain stimulation (NIBS) with high-frequency repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex of the lower leg and anodal transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex compared with rTMS alone in patients with Parkinson's disease (PD) with freezing of gait (FOG).
Study Details
Timeline
Interventions
Patients underwent five consecutive daily sessions of dual-mode NIBS with high-frequency repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex of the lower leg and anodal transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex simultaneously
Patients underwent five consecutive daily sessions of dual-mode NIBS with high-frequency repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex of the lower leg and sham anodal transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex simultaneously