At a glance
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The Effect of NO Precursors on Physiological Responses to Exercise
In Brief
A clinical study evaluating Nitrate, Nitrate and L-Arginine, and 4 other interventions for Physiology. Completed, enrolled 63 participants across 1 site.
Detailed Summary
NO is an ubiquitous molecule contributing to many physiological functions such as vasodilation, immune and oxidative stress responses. NO production can be supplemented either by providing substrate to the NO-synthase (L-Arginine and L-Citruline) or by providing nitrate which can lead to NO. In the present project the investigators evaluate the effect of various acute and chronic oral NO precursors supplementation on exercise performance and responses in healthy young and older subjects.
Study Details
Timeline
Interventions
Subjects will be supplemented orally either acutely or chronically (4-8 weeks) with NO precursors.
Subjects will be supplemented orally either acutely or chronically (4-8 weeks) with NO precursors.
Subjects will be supplemented orally either acutely or chronically (4-8 weeks) with NO precursors.
Subjects will be supplemented orally either acutely or chronically (4-8 weeks) with a placebo.
After the intake of the supplement. Concentration of hemoglobin (g/mL) in the quadriceps with the device : NIRS system Oxymon, ARTINIS.
After the intake of the supplement. Measure the stretching force in the ankle (N)