At a glance
ClinicalIndex Comparison RecordN/ACompleted· 15 enrolled
Drug / intervention
Ozone +2 moreother
Likely dose
Ozone at 0.06–0.08 ppm for 6.5 hoursAI-extracted
Key inclusion· 6
- ✓Ages 18–50 years
- ✓Peripheral oxygen saturation (SpO2) >94%
- ✓Systolic blood pressure 90–150 mm Hg
- ✓Diastolic blood pressure 60–100 mm Hg
Key exclusion· 5
- ✕Chronic medical conditions considered contraindication by PI, including significant cardiovascular disease, diabetes requiring medication, chronic renal disease, chronic thyroid disease
- ✕Use of systemic or inhaled steroids
- ✕Use of NSAID or aspirin within 7 days of each study visit, or inability to withhold prior to study sessions
- ✕Pregnant or nursing women
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Human Biological Responses to Low Level Ozone
In Brief
A clinical study evaluating Ozone, Filtered Air, and 1 other intervention for Environmental Exposure and Nasal Inflammation. Completed, enrolled 15 participants across 1 site.
Detailed Summary
To investigate if low level ozone exposure will cause measurable inflammation in nasal cells.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsEnvironmental Exposure, Nasal Inflammation
CountriesUnited States
CollaboratorsEnvironmental Protection Agency (EPA)
Timeline
N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedAug 2016
Enrollment StartApr 2017
Primary CompletionMay 2019
Study CompletionJul 2019
TodayJul 2026
First PostedAug 5, 2016
Enrollment StartApr 22, 2017
Primary CompletionMay 1, 2019
Study CompletionJul 1, 2019
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 9.9 years ago
Interventions
Ozoneother
Participants will be exposed to a concentration of ozone for 6.5 hours at a concentration that varies 0.06 to 0.08
Filtered Airother
Participants will be exposed to filtered clean air
Health and Exposure Tracker (HET)device
Ozone and heart rate tracker