At a glance
ClinicalIndex Comparison Record- ✓Age 18-65 years inclusive
- ✓Self-reported history of dentinal hypersensitivity lasting more than six months but not more than 10 years
- ✓Good general oral health with a minimum of 20 natural teeth
- ✓Minimum of 2 accessible non-adjacent teeth (incisors, canines, or pre-molars) with signs of facial/cervical gingival recession and/or signs of erosion or abrasion, no clinically significant gingival inflammation, tooth mobility ≤1, and sensitivity on evaporative air assessment (Schiff sensitivity score ≥1) at Screening
- ✕Pregnant, intending to become pregnant during the study, or breastfeeding
- ✕Known or suspected intolerance or hypersensitivity to study materials or ingredients
- ✕Participation in another clinical study within 30 days of screening, previous participation in this study, or participation in another tooth desensitizing treatment study within 8 weeks of screening
- ✕Recent history (within the last year) of alcohol or other substance abuse
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Study to Evaluate the Efficacy of an Experimental Occlusion Technology Dentifrice in the Relief of Dentinal Hypersensitivity
In Brief
A clinical study evaluating Stannous fluoride (SnF2) and Sodium monofluorophosphate (SMFP) for Dentin Sensitivity. Completed, enrolled 135 participants across 1 site.
Detailed Summary
This study will evaluate the effectiveness of an experimental dentifrice containing stannous fluoride, an established dentine tubule occlusion technology, at reducing dentine hypersensitivity (DH) compared to a negative control dentifrice. The test and control dentifrices will be administered for a total of 8 weeks, with assessments (via evaporative air and tactile stimuli) at baseline, and after 4 and 8 weeks twice-daily use.
Study Details
Timeline
Interventions
Dentifrice containing 0.454% weight by weight (w/w) SnF2 and 0.072% w/w NaF
Dentifrice containing 1400 ppm fluoride as SMFP