CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 34 enrolled
Drug / intervention
non surgical periodontal therapyprocedure
Likely dose
Not stated in record
Key inclusion· 4
  • ✓≥14 functional teeth
  • ✓Systemically healthy
  • ✓No prior surgical or non-surgical periodontal therapy
  • ✓No recent antibiotics or NSAIDs
Key exclusion· 2
  • ✕Smokers
  • ✕Pregnant females

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02861937
NCT02861937N/ACompleted
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Estimation of Interleukin-21 Levels in Gingival Crevicular Fluid in Patients With Periodontal Health and Disease Following Non-surgical Periodontal Therapy: A Clinico-biochemical Study

Krishnadevaraya College of Dental Sciences & Hospital·interventional·Posted Aug 10, 2016·Updated Sep 2, 2020

In Brief

A clinical study evaluating non surgical periodontal therapy for Chronic Peridontitis Patients and 2 related conditions. Completed, enrolled 34 participants.

Detailed Summary

Human IL-21 is present in gingival crevicular fluid in periodontal health, gingivitis and chronic periodontitis. A significant increase in the concentration of IL-21 in gingival crevicular fluid is observed with an increase in the amount of periodontal destruction. Non- surgical periodontal therapy aided in decrease of GCF IL-21 levels in clinical gingivitis and chronic periodontitis

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsChronic Peridontitis Patients, Chronic Gingivitis, Healthy
Countries--
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedAug 10, 2016
Enrollment StartApr 1, 2014
Primary CompletionSep 1, 2014
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 9.9 years ago

Interventions

non surgical periodontal therapyprocedure

and root planing (SRP) was performed in two to four appointments lasting approximately 60 minutes each under local anaesthesia (2% lignocaine hydrochloride with 1:2,00,000 adrenaline) using area specific Gracey periodontal curettes and an ultrasonic device. The treatment was concluded in 3 weeks. Within the duration of the study, all subjects received supportive therapy, which included professional plaque control and reinstruction of oral hygiene.