CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 181 enrolled
Drug / intervention
Obinutuzumab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02867384
NCT02867384Phase 2Completed

A Randomized Phase 2 Study of Obinutuzumab for Prevention of Chronic Graft-vs.-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation

Dana-Farber Cancer Institute·interventional·Posted Aug 15, 2016·Updated Feb 19, 2026

In Brief

A Phase 2 clinical trial evaluating Obinutuzumab and Placebo for Graft vs. Host Disease. Completed, enrolled 181 participants across 5 sites.

Detailed Summary

This research study is studying a drug called obinutuzumab as a means of preventing chronic Graft vs. Host Disease (cGVHD).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsRoche-Genentech

Timeline

Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedAug 15, 2016
Enrollment StartNov 29, 2016
Primary CompletionNov 29, 2023
Study CompletionNov 14, 2024
TodayJul 2, 2026
Enrollment to primary: 7 yearsPosted 9.9 years ago

Interventions

Obinutuzumabdrug

B cell depletion

Placebodrug

Placebo