CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 110 enrolled
Drug / intervention
Conjugated equine estrogen topical cream +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02869165
NCT02869165Phase 4Completed

The Effects of Vaginal Estrogen and a Nonhormonal Alternative on the Vaginal and Urinary Microbiome in Women With Genitourinary Syndrome of Menopause: A Randomized Controlled Trial

University of Louisville·interventional·Posted Aug 16, 2016·Updated May 18, 2021

In Brief

A Phase 4 clinical trial evaluating Conjugated equine estrogen topical cream and Apricot kernel oil for Atrophic Vaginitis and 2 related conditions. Completed, enrolled 110 participants across 1 site.

Detailed Summary

A randomized controlled trial looking at the effects of vaginal estrogen and a nonhormonal alternative on the vaginal and urinary microbiome in women with genitourinary syndrome of menopause.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2017201820192020202120222023202420252026
First PostedAug 16, 2016
Enrollment StartJan 1, 2017
Primary CompletionJun 30, 2018
Study CompletionDec 31, 2019
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 9.9 years ago

Interventions

Conjugated equine estrogen topical creamdrug

Comparison of the bacterial communities in the vagina and urine of postmenopausal women who use Premarin vaginal cream versus apricot kernel oil and to themselves before and after use.

Apricot kernel oildrug

Comparison of the bacterial communities in the vagina and urine of postmenopausal women who use Premarin vaginal cream versus apricot kernel oil and to themselves before and after use.