CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 12 enrolled
Drug / intervention
Albutein 5% +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02872142
NCT02872142Phase 2Completed

Pilot Study to Evaluate the Efficacy and Safety of Plasma Exchange With Albutein® 5% in Patients With Amyotrophic Lateral Sclerosis

Grifols Therapeutics LLC·interventional·Posted Aug 19, 2016·Updated May 5, 2021

In Brief

A Phase 2 clinical trial evaluating Albutein 5% and Plasma Exchange for Amyotrophic Lateral Sclerosis. Completed, enrolled 12 participants across 1 site.

Detailed Summary

This is a pilot, phase 2, prospective, open-label, single-arm study to evaluate disease progression, forced vital capacity, and the safety and tolerability of plasma exchange (PE) using Albutein® 5% in participants with amyotrophic lateral sclerosis (ALS).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedAug 19, 2016
Enrollment StartAug 29, 2016
Primary CompletionAug 15, 2019
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 9.9 years ago

Interventions

Albutein 5%biological

Albutein is manufactured from human plasma. The dose of Albutein 5% for replacement following plasma removal will be calculated based on gender, weight, and the hematocrit of the participant.

Plasma Exchangeprocedure

Plasma Exchange will be performed using albutein 5% as the replacement solution.