CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 12 enrolled
Drug / intervention
Netarsudil ophthalmic solution 0.02% +1 moredrug
Likely dose
Netarsudil 0.02% ophthalmic solution once daily in both eyes in the evening for 7 daysAI-extracted
Key inclusion· 4
  • Age ≥18 years
  • Ocular hypertension or open-angle glaucoma in both eyes
  • Unmedicated intraocular pressure >17 mmHg in one or both eyes AND <30 mmHg in both eyes
  • Corrected visual acuity ≥20/200 in each eye
Key exclusion· 8
  • Glaucoma with pseudoexfoliation or pigment dispersion component
  • History of angle closure or narrow angles
  • Intraocular pressure ≥30 mmHg
  • Ocular medications within 30 days

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02874846
NCT02874846Phase 2Completed

A Double-masked, Randomized, Placebo-controlled Study of the Nocturnal and Diurnal IOP-lowering Effect of Netarsudil Ophthalmic Solution 0.02% in Habitual Positions Over a 24-hour Period.

Aerie Pharmaceuticals·interventional·Posted Aug 22, 2016·Updated Apr 17, 2018

In Brief

A Phase 2 clinical trial evaluating Netarsudil ophthalmic solution 0.02% and Netarsudil Ophthalmic Solution Vehicle for Ocular Hypertension and Open Angle Glaucoma. Completed, enrolled 12 participants across 1 site.

Detailed Summary

To evaluate effect of Netarsudil Ophthalmic Solution 0.02% on Nocturnal and Diurnal Intraocular Pressure.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedAug 22, 2016
Enrollment StartJul 1, 2016
Primary CompletionSep 1, 2016
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 9.9 years ago

Interventions

Netarsudil ophthalmic solution 0.02%drug

Once daily in both eyes (OU) in the evening (PM) for 7 days

Netarsudil Ophthalmic Solution Vehicleother

Once daily in both eyes (OU) in the evening (PM) for 7 days