CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 125 enrolled
Drug / intervention
Single shot interscalene nerve block +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02876055
NCT02876055Phase 4Completed

Prospective, Randomized Controlled Trial Comparing Analgesic Efficacy of Single Injection vs. Continuous Interscalene Blockade vs. Local Infiltration Analgesia for Patients Undergoing Primary Total Shoulder Arthroplasty

Mayo Clinic·interventional·Posted Aug 23, 2016·Updated Apr 16, 2019

In Brief

A Phase 4 clinical trial evaluating Single shot interscalene nerve block, Continuous interscalene nerve block, and 1 other intervention for Pain, Postoperative. Completed, enrolled 125 participants across 1 site.

Detailed Summary

Total shoulder arthroplasty (TSA) is considered to be a major surgical procedure resulting in severe postoperative pain, especially in the first 48 hours after surgery. The use of interscalene brachial plexus nerve block remains the cornerstone for analgesia following shoulder surgery; however, with the advent of local infiltration analgesia (LIA), there has been increasing interest in its use for total joint arthroplasty. Since the benefits of local infiltration analgesia within a comprehensive multi-modal analgesia clinical pathway have yet to be established for total shoulder arthroplasty, the Investigators plan to assess and compare analgesia outcomes between three intervention groups: single shot interscalene brachial plexus block (SISB), continuous interscalene brachial plexus block (CISB), and local infiltration analgesia (LIA).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2017201820192020202120222023202420252026
First PostedAug 23, 2016
Enrollment StartNov 1, 2016
Primary CompletionFeb 1, 2018
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 9.9 years ago

Interventions

Single shot interscalene nerve blockdrug

Peripheral regional anesthesia nerve block - Single shot interscalene nerve block

Continuous interscalene nerve blockdrug

Peripheral regional anesthesia nerve block - continuous catheter interscalene nerve block

Local Infiltration Analgesia (LIA)drug

Injection of local anesthetic into the peri-articular tissues and intra-articular capsule in a systematic approach for orthopedic surgery