At a glance
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Effects of Broccoli Sprout Extract on Allergic Rhinitis
In Brief
A Phase 2 clinical trial evaluating Broccoli Sprout Extract, fluticasone nasal, and 2 other interventions for Rhinitis,Allergic. Completed, enrolled 47 participants across 1 site.
Detailed Summary
Allergic rhinitis is a common illness suffered among US Veterans. There are medications that help relieve allergy symptoms, including nasal steroid sprays and antihistamines. Some patients have increase symptoms with exposure to their trigger, such as a grasses when combined with pollution due to oxidative stress from pollution. In this study, patients with allergic rhinitis to grass will be given broccoli sprout extract that contains an antioxidant sulforaphane do see if there is beneficial effect in these patients.
Study Details
Timeline
Interventions
Broccoli Sprout Extract contains the antioxidant Sulforaphane which is the active ingredient being studies.
fluticasone is a nasal steroid that is currently approved for treatment of allergic rhinitis.
a tablet similar to the actual broccoli sprout extract though without BSE.
normal saline to replace nasal fluticasone in specific arms of the study