CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 3,580 enrolled
Drug / intervention
Prize incentive - Low +9 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02890459
NCT02890459N/ACompleted

Innovative Incentive Strategies for Sustainable HIV Testing and Antiretroviral Treatment

University of California, San Francisco·interventional·Posted Sep 7, 2016·Updated Feb 24, 2022

In Brief

A clinical study evaluating Prize incentive - Low, Prize incentive - High, and 8 other interventions for HIV/AIDS. Completed, enrolled 3,580 participants across 1 site.

Detailed Summary

The success of combination HIV prevention efforts, including HIV treatment as prevention, hinges on universal, routine HIV testing with effective treatment after HIV diagnosis. The proposed study will evaluate the comparative effectiveness and sustainability of innovative incentive strategies, informed directly by behavioral economics and decision psychology, to promote HIV testing among men and HIV treatment among HIV-infected adults in rural Uganda.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHIV/AIDS
CountriesUganda

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedSep 7, 2016
Enrollment StartApr 1, 2016
Primary CompletionAug 21, 2019
Study CompletionJan 3, 2020
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 9.8 years ago

Interventions

Prize incentive - Lowother

Low expected prize value.

Prize incentive - Highother

High expected prize value.

Escalating payment incentiveother

The incentives will increase in value when participants are found to meet the pre-specified virologic suppression criteria at 6 weeks, 3 months and 6 months. If the virologic threshold for an incentive is missed at the 6 week or 3 month time-point, the subsequent incentive for an undetectable HIV viral load will be reset to the initial incentive value.

Travel Voucherother

Travel voucher to assist with linkage to care.

Standard careother

Includes HIV viral load and treatment adherence counseling.

Fixed Incentive - Prizebehavioral

Men are informed that if they come for HIV testing, they will receive a specific prize (gain framing). The prize will be an item worth the same amount in US dollars as loss aversion and the expected value of a lottery prize. This gain-framed incentive resembles the form that incentives usually take in most studies and serves as a comparison to the lottery-based and loss-framed incentives.

Loss Aversion - Prizebehavioral

The prizes are worth approximately the same amount as the fixed incentive and expected value of a lottery prize. At the time of randomization, study staff will inform the participant that he has won a prize. Staff will ask the participant to choose a specific prize from several choices, and then provide an opportunity for the participant to see the prize. Study staff will then tell participants that they will lose the prize if they do not participate in HIV testing. In this way, the incentive is framed as a loss rather than a gain, thereby leveraging loss aversion while not requiring men in very low-income settings to experience an actual loss.

Lottery - Prizebehavioral

Men are entered in a lottery that offers a chance to win high-value prizes after testing for HIV at a community health campaign. Staff will emphasize that only those who come for HIV testing will be entered into the lottery and that not everyone will win a prize. Participants were informed at enrollment about the list of prizes and corresponding probabilities of winning them, in terms that are understandable to men with low numeracy (e.g., "1 in 20" rather than 5%). The probabilities of winning prizes varied between 1-5%, with higher value prizes having lower probability.

Fixed Incentive - Voucherbehavioral

A standard gain-framed incentive arm in which participants will be offered a voucher for coming for a repeat HIV test in the future.

Loss Aversion - Depositbehavioral

A loss-aversion framed incentive in which participants will be asked to voluntarily make a deposit that can be retrieved, with interest on the deposit, if they come for an HIV test in the future (i.e. for repeat testing)