CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 550 enrolled
Drug / intervention
inspiratory muscle strengthprocedure
Likely dose
Not stated in record
Key inclusion· 4
  • Age 18 years or older
  • Spinal cord injury with AIS grade A, B, C, or D
  • Lesion level between C1 and T12
  • Enrolled during initial rehabilitation phase after SCI
Key exclusion· 3
  • Known neurological diseases such as multiple sclerosis or ALS
  • Requiring 24-hour mechanical ventilation
  • Significant mental disorders

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02891096
NCT02891096N/ACompleted

Inspiratory Muscle Strength and Respiratory Complications After Spinal Cord Injury: a Multicenter, Prospective Cohort Study

Swiss Paraplegic Research, Nottwil·observational·Posted Sep 7, 2016·Updated Feb 24, 2025

In Brief

An observational study evaluating inspiratory muscle strength for Spinal Cord Injuries and Pneumonia. Completed, enrolled 550 participants across 1 site.

Detailed Summary

The investigators conducting this study to investigate the relation between the respiratory muscle strength and respiratory complications. To understand more about respiratory complications the influence of different factors (such as in- and expiratory muscle strength, lung function parameters, physical activity, smoking, medications,…) on respiratory complications (such as pneumonia) will be investigated.

Study Details

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedSep 7, 2016
Enrollment StartOct 1, 2016
Primary CompletionOct 31, 2021
TodayJul 2, 2026
Enrollment to primary: 5.1 yearsPosted 9.8 years ago

Interventions

inspiratory muscle strengthprocedure

Measurements: * in- and expiratory muscle strength (5min) * lung function (FVC, FEV1, PEF, PCF) (10 min) Questionnaires: * ISCoS core data-set * ISCoS pulmonary function data sets * ISCoS quality of life questionnaire * questionnaire on individual respiratory muscle training, regular physical exercise and therapies * individual medication/vaccination and other medical complications will be assessed from patient's medical records All measurements will be performed at each of the 4 measurement time-points (up to 4 times during inpatient rehabilitation) and last about 40 min per patient and measurement time-point in total (time with patient).