At a glance
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Optimizing Tobacco Dependence Treatment in the Emergency Department
In Brief
A Phase 3 clinical trial evaluating Brief Negotiated Interview (BNI), Nicotine replacement therapy (NRT), and 2 other interventions for Tobacco Use Disorder. Completed, enrolled 1,056 participants across 1 site.
Detailed Summary
The investigators propose an innovative full-factorial design in a cohort of 1056 adult smokers in an urban emergency department (ED), to test the efficacy of four key intervention components: motivational interviewing, medication, quitline referral, and texting. At the trial's completion, a mixed-methods approach will be used to identify the components that were efficacious within the proposed cost constraint, along with feasibility and acceptability to providers and subjects. The investigators will then assemble an intervention that maximizes efficacy, given a cost-effectiveness constraint and findings from a qualitative analysis.
Study Details
Timeline
Interventions
Brief motivational interview on smoking behavior
6 weeks of nicotine replacement, patches and gum. First dose of each started in ED. Patches are 14mg or 21 mg. Gum is 2mg per piece.
Faxed referral to the CT Smokers Quitline for the subject. QL will then call subject to offer phone based counseling.
Enrollment in a version of NCI's SmokefreeTxt, tailored for the study.