At a glance
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A Pilot Study of Intravenous Ascorbic Acid and Folfirinox in the Treatment of Advanced Pancreatic Cancer
In Brief
A Early Phase 1 clinical trial evaluating Oxaliplatin, Irinotecan Hydrochloride, and 3 other interventions for Pancreatic Adenocarcinoma and 4 related conditions. Completed, enrolled 8 participants across 1 site.
Detailed Summary
This pilot clinical trial studies the side effects of ascorbic acid and combination chemotherapy in treating patients with pancreatic cancer that has spread to other places in the body, has come back, or cannot be removed by surgery. Nutrients found in food and dietary supplements, such as ascorbic acid, may improve the tolerability of chemotherapy regimens. Drugs used in chemotherapy, such as fluorouracil, irinotecan hydrochloride, and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving ascorbic acid and combination chemotherapy may work better in treating patients with pancreatic cancer.
Study Details
Timeline
Interventions
Given IV
Given IV
Given IV
Given IV
Given IV