CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 250 enrolled
Drug / intervention
Bimekizumab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02905006
NCT02905006Phase 2Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose Ranging Study to Evaluate the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

UCB Biopharma S.P.R.L.·interventional·Posted Sep 19, 2016·Updated Jul 21, 2022

In Brief

A Phase 2 clinical trial evaluating Bimekizumab and Placebo for Chronic Plaque Psoriasis. Completed, enrolled 250 participants across 41 sites in 6 countries.

Detailed Summary

This is a Phase 2b, multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose ranging study to investigate the safety, efficacy, pharmacokinetics (PK), and pharmacodynamics (PD) of Bimekizumab compared with placebo in adult subjects with moderate to severe chronic plaque psoriasis in order to guide the selection of doses and clinical indices in the Phase 3 development program.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, Czechia, Hungary, Japan, Poland, United States
CollaboratorsParexel

Timeline

Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedSep 19, 2016
Enrollment StartAug 1, 2016
Primary CompletionJun 1, 2017
Study CompletionJul 1, 2017
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 9.8 years ago

Interventions

Bimekizumabdrug

Subjects will be randomized to receive a combination of injections of Bimekizumab.

Placeboother

Subjects randomized to the placebo group, will receive a combination of several injections of Placebo to maintain the blinding.