CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 110 enrolled
Drug / intervention
Retinol +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02906566
NCT02906566Phase 4Completed
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Discovery of Effects of Retinol on Human Skin Aging in Individuals of East Asian Descent

Stanford University·interventional·Posted Sep 20, 2016·Updated Apr 16, 2019

In Brief

A Phase 4 clinical trial evaluating Retinol and Placebo for Intrinsic Aging of Skin. Completed, enrolled 110 participants across 1 site.

Detailed Summary

There has been increasing evidence for different rates of natural aging in humans and one of the best organs to study human aging is skin. Studies have demonstrated anti-aging effects of topical agents (such as creams, gels, lotions, or ointments) and one of them, retinol or vitamin A, was shown to decrease fine wrinkling in skin of older individuals. Additionally, studies of retinol in humans have largely occurred in white populations and so this study aims to focus on skin aging in individuals of East Asian descent as they represent a majority of the world population. This study aims to better characterize the molecular basis of rejuvenation effects and to potentially discover new topical agents with similar and/or more effective preservation of skin youthfulness.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIntrinsic Aging of Skin
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20162017201820192020202120222023202420252026
First PostedSep 20, 2016
Enrollment StartNov 1, 2015
Primary CompletionMar 9, 2018
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 9.8 years ago

Interventions

Retinoldrug

Retinol in the form of vitamin A lotion

Placebodrug

Placebo of Retinol