CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 84 enrolled
Drug / intervention
triple antibiotic paste with an anti-inflammatory drugother
Likely dose
Triple antibiotic paste (ciprofloxacin, metronidazole, minocycline) with diclofenac potassium 50 mg (Catafast) as intracanal medicationAI-extracted
Key inclusion· 5
  • ✓Age 18–50 years
  • ✓Both male and female
  • ✓Medically healthy with no systemic disease
  • ✓Mandibular or maxillary single-rooted teeth
Key exclusion· 7
  • ✕Acute dentoalveolar abscess
  • ✕More than one tooth requiring root canal treatment
  • ✕Analgesic, anti-inflammatory, or antibiotic use in prior 10 days
  • ✕Pregnant females

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02907489
NCT02907489Phase 1Completed
CompareCT.gov

The Effect of Triple Antibiotic Paste as an Intracanal Medication With an Anti-Inflammatory Drug on Post-Operative Pain of Asymptomatic Uniradicular Necrotic Teeth (A Double Blind Randomized Clinical Trial).

Cairo University·interventional·Posted Sep 20, 2016·Updated Sep 24, 2019

In Brief

A Phase 1 clinical trial evaluating triple antibiotic paste with an anti-inflammatory drug for Asymptomatic Necrotic Teeth. Completed, enrolled 84 participants.

Detailed Summary

The purpose of this study is to determine whether the use of triple antibiotic paste as intracanal medication with an anti-inflammatory drug, compared to a calcium hydroxide will reduce postoperative pain and intracanal bacteria or not in patients with asymptomatic necrotic teeth.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAsymptomatic Necrotic Teeth
Countries--
Collaborators--

Timeline

Phase 1CompletedFinished
2017201820192020202120222023202420252026
First PostedSep 20, 2016
Enrollment StartOct 1, 2016
Primary CompletionApr 1, 2018
Study CompletionJul 1, 2018
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 9.8 years ago

Interventions

triple antibiotic paste with an anti-inflammatory drugother

Mixture of ciprofloxacin, metronidazole and minocycline.and diclofenac potassium 50 mg (Catafast)