At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 203 enrolled
Drug / intervention
Control toothpaste containing Novamin® technology +8 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Clinical Efficacy in Relieving Dentin Hypersensitivity of Nanohydroxyapatite-Containing Toothpastes and Cream
The University of Texas Health Science Center at San Antonio·interventional·Posted Sep 29, 2016·Updated Nov 16, 2018
In Brief
A Phase 2 clinical trial evaluating Control toothpaste containing Novamin® technology, Control toothpaste containing 1500 ppm fluoride as MFP, and 7 other interventions for Dentin Sensitivity. Completed, enrolled 203 participants across 1 site.
Detailed Summary
This study will investigate the effectiveness of nanohydroxyapatite (nano-HAP)-containing toothpastes and cream to relieve dentin hypersensitivity, comparing it with those of a commercial desensitizing dentifrice containing calcium sodium phosphosilicate (Novamin® technology) and a standard fluoride dentifrice containing 1,500 ppm fluoride as sodium monofluorophosphate (MFP).
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDentin Sensitivity
CountriesUnited States
CollaboratorsSangi Co., Ltd.
Timeline
Phase 2CompletedFinished
20162017201820192020202120222023202420252026
Enrollment StartMay 2015
Primary CompletionSep 2016
First PostedSep 2016
TodayJul 2026
First PostedSep 29, 2016
Enrollment StartMay 1, 2015
Primary CompletionSep 1, 2016
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 9.8 years ago
Interventions
Control toothpaste containing Novamin® technologydrug
Control toothpaste containing 1500 ppm fluoride as MFPdrug
Test toothpaste with nano-HAP (high concentration)drug
Test toothpaste with nano-HAP (low concentration)drug
Test toothpaste with nano-HAP and (Potassium Nitrate) KNO3drug
Control toothpaste without nano-HAPdrug
Test toothpaste with nano-HAP (medium concentration)drug
Test cream with nano-HAP (higher concentration)drug
Control cream without nano-HAPdrug