CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 13 enrolled
Drug / intervention
R21/Matrix-M1 +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02925403
NCT02925403Phase 2Completed

A Phase Ib Randomised, Controlled, Single-blind Study to Assess the Safety, Immunogenicity of the Malaria Vaccine Candidate R21 With Matrix-M1 Adjuvant in West African Adult Volunteers

University of Oxford·interventional·Posted Oct 5, 2016·Updated Nov 6, 2019

In Brief

A Phase 2 clinical trial evaluating R21/Matrix-M1 and Saline for Malaria. Completed, enrolled 13 participants across 1 site.

Detailed Summary

This is a study in which healthy adult volunteers will be given either an experimental Malaria vaccine or a saline control vaccine. Each volunteer will receive three vaccinations in total. Volunteers will be randomly allocated to one of two groups: Group 1 will receive a low dose of the Malaria vaccine on days 0, 28, and 56. Group 2 will receive a saline solution on days 0, 28, and 56.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMalaria
CountriesBurkina Faso
Collaborators--

Timeline

Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedOct 5, 2016
Enrollment StartAug 26, 2016
Primary CompletionFeb 15, 2017
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 9.7 years ago

Interventions

R21/Matrix-M1biological

Salineother