At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Multi-institution Phase II Trial of Intraoperative Electron Beam Radiotherapy Boost at the Time of Breast Conserving Surgery With Oncoplastic Reconstruction in Women With Early-Stage Breast Cancer
In Brief
A Phase 2 clinical trial evaluating Electron Beam Therapy, Lumpectomy, and 4 other interventions for Stage IA Breast Cancer and 3 related conditions. Active but no longer recruiting, targeting 108 participants across 5 sites in 2 countries.
Signals
Detailed Summary
This phase II trial studies the side effects of intraoperative electron beam radiotherapy boost and to see how well it works in treating patients with stage I-II breast cancer undergoing surgery with reconstruction. Giving a single dose of electron beam radiation to the tumor cavity during the breast surgery before reconstruction may be a better way to kill tumor cells and shrink tumors.
Study Details
Timeline
Arms & Interventions
Patients undergo standard of care lumpectomy and then undergo 1 fraction of IOERT boost to the lumpectomy cavity. Patients then undergo standard of care oncoplastic reconstruction and whole breast radiation therapy.
Interventions
Undergo IOERT boost
Undergo lumpectomy
Ancillary studies
Ancillary studies
Undergo whole breast radiation therapy
Undergo oncoplastic reconstruction