CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 83 enrolled
Drug / intervention
Experimental Denture Adhesive +1 moredevice
Likely dose
Experimental denture adhesive: 3 continuous strips on upper denture and 1 continuous strip on lower denture, single applicationAI-extracted
Key inclusion· 5
  • Age 18–85 years inclusive
  • Full dentures in both upper and lower arch that are well-fitting and well-made
  • Dentures have adequate retention and stability (Kapur Retention and Stability Index Sum Score ≥6)
  • Participant reports food trapped under dentures and has peanut particle migration rating >0 at screening
Key exclusion· 10
  • Pregnant or intending to become pregnant during study
  • Breastfeeding
  • History of swallowing difficulties or choking
  • Xerostomia (dry mouth) caused by current condition or medication

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02928380
NCT02928380N/ACompleted

A Clinical Study to Evaluate the Ability of an Experimental Denture Adhesive to Prevent Food Particle Ingress Under Dentures

GlaxoSmithKline·interventional·Posted Oct 10, 2016·Updated Aug 27, 2018

In Brief

A clinical study evaluating Experimental Denture Adhesive and Reference (Marketed) Denture Adhesive for Denture Retention. Completed, enrolled 83 participants across 1 site.

Detailed Summary

In this clinical study, an experimental denture adhesive with a precision tip nozzle was tested to evaluate the relative efficacy to reduce the ingress of food under the denture compared to use of no adhesive or a standard marketed adhesive.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedOct 10, 2016
Enrollment StartJul 25, 2016
Primary CompletionSep 1, 2016
Study CompletionSep 16, 2016
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 9.7 years ago

Interventions

Experimental Denture Adhesivedevice

Participants received a single application of test denture adhesive with a Flat Ribbon Nozzle as 3 Continuous strips those were applied to upper denture and one continuous strip that was applied to the lower denture which were placed in the mouth.

Reference (Marketed) Denture Adhesivedevice

Participants received a single application of marketed denture adhesive with a flat ribbon nozzle as a 3 dabs those were applied to upper denture and 2 dabs those were applied to lower denture, which were placed in the mouth.