CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 34 enrolled
Drug / intervention
Apple polyphenols +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02940249
NCT02940249N/ACompleted
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Dose-response Effect of an Apple Extract on Postprandial Glycaemia: a Randomised Controlled Trial. The GLU-POMME Study.

King's College London·interventional·Posted Oct 20, 2016·Updated Jun 17, 2020

In Brief

A clinical study evaluating Apple polyphenols and Placebo for Prevention of Hyperglycaemia. Completed, enrolled 34 participants across 1 site.

Detailed Summary

Postprandial hyperglycaemia can lead to adverse modifications to functional proteins within the body and eventually lead to the development of type 2 diabetes. Previous research by this group has shown that an apple polyphenol extract reduced hyperglycaemia following a high-carbohydrate meal. The aim of this study is to investigate the effects of lower doses of the apple extract on postprandial glycaemia, insulinaemia and plasma gastric inhibitory polypeptide concentrations following a mixed carbohydrate test meal.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPrevention of Hyperglycaemia
CountriesUnited Kingdom
CollaboratorsDIANA Food

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedOct 20, 2016
Enrollment StartJan 1, 2017
Primary CompletionNov 1, 2017
Study CompletionFeb 1, 2018
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 9.7 years ago

Interventions

Apple polyphenolsdietary

Drinks will be delivered in random order at 4 separate study visits immediately before a high-carbohydrate meal. Seven days wash-out period will be required between study days.

Placebodietary