CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 66 enrolled
Drug / intervention
Oxytocin +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02941692
NCT02941692Phase 2Completed
CompareCT.gov

The Effects of Oxytocin on Couples Conflict Resolution Interactions

Medical University of South Carolina·interventional·Posted Oct 21, 2016·Updated Oct 12, 2018

In Brief

A Phase 2 clinical trial evaluating Oxytocin and Placebo for Substance Misuse and 2 related conditions. Completed, enrolled 66 participants.

Detailed Summary

Oxytocin is a promising new medication found to have positive effects on prosocial behavior, reduce negative affect such as fear and anxiety, and reduce stress-induced addictive behaviors. This study aims to investigate the extent to which a 40 IU dose of intranasal oxytocin improves couples' conflict resolution skills and subjective, physiological, and neuroendocrine responses to conflict. Conflict resolution discussions will take place in the laboratory and will be videotaped.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSubstance Misuse, Interpersonal Conflict, Neuroendocrine Reactivity
Countries--
CollaboratorsNational Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedOct 21, 2016
Enrollment StartJun 1, 2014
Primary CompletionMar 1, 2017
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 9.7 years ago

Interventions

Oxytocindrug

Placebodrug

Placebo for Oxytocin