At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 40 enrolled
Drug / intervention
Neem leaf extract +1 moredrug
Likely dose
Chlorhexidine gluconate 2%from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Resolution of Pain and Swelling After the Use of Neem Leaf Extract (Azadirachta Indica) Compared to Chlorhexidine Gluconate as an Intracanal Irrigant in Necrotic Primary Molar Teeth in Children Undergoing Pulpectomy Treatment: A Randomised Controlled Trial
In Brief
A Phase 3 clinical trial evaluating Neem leaf extract and Chlorhexidine gluconate for Periapical Abscess. Completed, enrolled 40 participants across 1 site.
Detailed Summary
The trial is to test the resolution of pain, swelling and other signs of periapical infection and the antimicrobial efficacy when using the neem leaf extract compared to chlorhexidine as root canal irrigant in Pulpectomy treatment for children.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPeriapical Abscess
CountriesEgypt
Collaborators--
Timeline
Phase 3CompletedFinished
2017201820192020202120222023202420252026
First PostedOct 2016
Enrollment StartDec 2016
Primary CompletionFeb 2018
TodayJul 2026
First PostedOct 25, 2016
Enrollment StartDec 1, 2016
Primary CompletionFeb 1, 2018
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 9.7 years ago
Interventions
Neem leaf extractdrug
A natural irrigant solution act as anti-inflammatory and anti bacterial
Chlorhexidine gluconatedrug
2%chlorhexidine gluconate , anti bacterial root canal irrigant solution