CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 26 enrolled
Drug / intervention
Atrioventricular junctional (AVJ) ablation +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02946853
NCT02946853N/ACompleted
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Junctional AV Ablation in CRT-D Patients With Atrial Fibrillation (JAVA-CRT Trial)

University of Rochester·interventional·Posted Oct 27, 2016·Updated Jan 25, 2022

In Brief

A clinical study evaluating Atrioventricular junctional (AVJ) ablation and Cardiac resynchronization therapy - defibrillator for Systolic Heart Failure and Atrial Fibrillation (Permanent). Completed, enrolled 26 participants across 21 sites.

Detailed Summary

Cardiac resynchronization therapy (CRT) is a demonstrably effective device intervention for patients with heart failure with reduced ejection fraction and specific indication. However, many patients with heart failure (HF) are unable to maintain sinus rhythm and approximately 30-36% of CRT patients are in atrial fibrillation (AF).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSystolic Heart Failure, Atrial Fibrillation (Permanent)
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedOct 27, 2016
Enrollment StartOct 1, 2016
Primary CompletionAug 31, 2020
TodayJul 2, 2026
Enrollment to primary: 3.9 yearsPosted 9.7 years ago

Interventions

Atrioventricular junctional (AVJ) ablationprocedure

RF energy delivery to AV node to create complete AV block

Cardiac resynchronization therapy - defibrillatordevice

Insertion of device capable of providing biventricular pacing and cardiac defibrillation