CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 44 enrolled
Drug / intervention
Standard Treatment +1 moreradiation
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02947984
NCT02947984Phase 3Completed
CompareCT.gov

Prospective Study Of Patients With Recurrent Or Incomplete Excised Benign Intercranial Meningiomas For The Evaluation Of Treatment Result With Combined Proton And Photon Irradiation To Doses 55.8 Or 63.0 CGE

Massachusetts General Hospital·interventional·Posted Oct 28, 2016·Updated Jun 14, 2017

In Brief

A Phase 3 clinical trial evaluating Standard Treatment and Higher Dose for Benign Meningioma. Completed, enrolled 44 participants across 1 site.

Detailed Summary

The purpose of this study is to determine the best radiation dose for participants with meningioma that has grown back after previous surgery, or which the surgeon has been unable to remove completely. This research study is designed to determine whether a higher dose of radiation will decrease the likelihood that the tumor will grow back, compared to the probability of re-growth that occurs after standard radiation doses.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBenign Meningioma
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
19992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedOct 28, 2016
Enrollment StartMar 1, 1999
Primary CompletionSep 1, 2016
TodayJul 2, 2026
Enrollment to primary: 17.5 yearsPosted 9.7 years ago

Interventions

Standard Treatmentradiation

55.8 CGE in 31 treatments of 1.8 CGE given once a day, for five days each week. Treatment based upon a treatment planning CT.

Higher Doseradiation

55.8 CGE in 31 treatments of 1.8 CGE given once a day, for five days each week. Treatment based upon a treatment planning CT.