CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 2,176 enrolled
Drug / intervention
Praluent (Alirocumab) +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02957682
NCT02957682Phase 4Completed

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of Praluent on Neurocognitive Function in Patients With Heterozygous Familial Hypercholesterolemia or With Non-Familial Hypercholesterolemia at High and Very High Cardiovascular Risk

Regeneron Pharmaceuticals·interventional·Posted Nov 8, 2016·Updated May 7, 2021

In Brief

A Phase 4 clinical trial evaluating Praluent (Alirocumab) and Placebo for Hypercholesterolemia. Completed, enrolled 2,176 participants across 188 sites in 9 countries.

Detailed Summary

The main purpose of this study is to evaluate the effect on mental state (known as "neurocognitive function") with use of Praluent.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBulgaria, Chile, Estonia, Japan, Mexico, Russia, South Africa, Ukraine, United States
CollaboratorsSanofi

Timeline

Phase 4CompletedFinished
2017201820192020202120222023202420252026
First PostedNov 8, 2016
Enrollment StartNov 2, 2016
Primary CompletionMar 5, 2020
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 9.7 years ago

Interventions

Praluent (Alirocumab)drug

Placebodrug