At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Evaluation of PCV Schedules in a Naive Population in Vietnam
In Brief
A Phase 4 clinical trial evaluating PCV 2p+1, PCV 3p+0, and 2 other interventions for Pneumonia, Pneumococcal. Completed, enrolled 18,652 participants across 1 site.
Detailed Summary
The cost of pneumococcal conjugate vaccine use can be greatly reduced by making use of existing herd immunity to protect children against vaccine type pneumococci. The investigators will reduce the circulation of vaccine type pneumococci to low levels by PCV catch-up campaign; vaccinating all children less than 3 years of age with PCV, after which the investigators will evaluate the ability of a simplified two doses regimen and an alternative one dose regimen to prevent the reintroduction of vaccine type pneumococci compared to the WHO recommended 2 doses schedule.
Study Details
Timeline
Interventions
introduction of PCV in a reduced dosing 2p+1 schedule
introduction of PCV in a reduced dosing 3p+0 schedule
introduction of PCV in a reduced dosing 1p+1 schedule
introduction of PCV in a reduced dosing 0p+1 schedule