CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 81 enrolled
Drug / intervention
Aspirin +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02965703
NCT02965703Phase 2Active

Evaluating Intermittent Dosing of Aspirin for Colorectal Cancer Chemoprevention

National Cancer Institute (NCI)·interventional·Posted Nov 17, 2016·Updated May 28, 2026

In Brief

A Phase 2 clinical trial evaluating Aspirin, Biospecimen Collection, and 3 other interventions for Colorectal Adenoma and Colorectal Carcinoma. Active but no longer recruiting, targeting 81 participants across 1 site.

Detailed Summary

This phase IIa trial studies how well aspirin works in preventing colorectal cancer in patients with colorectal adenoma. Aspirin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2Active
20172018201920202021202220232024202520262027
First PostedNov 17, 2016
Enrollment StartJan 16, 2018
Primary CompletionJan 31, 2023
Study CompletionDec 24, 2026
TodayJul 2, 2026
Enrollment to primary: 5.0 yearsPosted 9.6 years ago

Interventions

Aspirindrug

Given PO

Biospecimen Collectionprocedure

Undergo collection of blood, urine, stool, and rectal swab samples

Placebo Administrationother

Given PO

Questionnaire Administrationother

Ancillary studies

Rectal Biopsyprocedure

Undergo rectal biopsy