CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 27 enrolled
Drug / intervention
Bihormonal Bionic Pancreas +3 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02969863
NCT02969863N/ACompleted

The Monitoring Study: Evaluating the Effect of Remote Monitoring For Hypoglycemia on Bionic Pancreas Safety and Efficacy

Massachusetts General Hospital·interventional·Posted Nov 21, 2016·Updated Jul 30, 2018

In Brief

A clinical study evaluating Bihormonal Bionic Pancreas, Insulin Only Bionic Pancreas, and 2 other interventions for Type1diabetes. Completed, enrolled 27 participants across 1 site.

Detailed Summary

To conduct an outpatient study testing two configurations of the bionic pancreas (bi-hormonal and insulin-only) with and without remote monitoring of hypoglycemia in 25 adult (≥ 18 years of age) subjects with type 1 diabetes in a random-order crossover study versus usual care with an insulin pump with and without remote monitoring of hypoglycemia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType1diabetes
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedNov 21, 2016
Enrollment StartApr 1, 2017
Primary CompletionJun 1, 2017
Study CompletionDec 28, 2017
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 9.6 years ago

Interventions

Bihormonal Bionic Pancreasdevice

Participants will wear a Bionic Pancreas that uses glucagon and insulin (bihormonal) to automate their glucose control based on continuous glucose monitor readings.

Insulin Only Bionic Pancreasdevice

Participants will wear a Bionic Pancreas that uses just insulin (insulin-only) to automate their glucose control based on continuous glucose monitor readings.

Monitored for Hypoglycemiaother

During half of the study arms (one each bihormonal bionic pancreas, insulin-only bionic pancreas and usual care) the subjects will be remotely monitored for device connectivity and hypoglycemia, and will be notified by study staff any time their continuous glucose monitor reads less than 50 mg/dl for 15 mintues.

Not Monitored for Hypoglycemiaother

During half of the study arms (one each bihormonal bionic pancreas, insulin-only bionic pancreas and usual care) the subjects will be remotely monitored for device connectivity only, not hypoglycemia.