CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 29 enrolled
Drug / intervention
MGCD516drug
Likely dose
MGCD516 150 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02978859
NCT02978859Phase 2Completed

A Phase II Trial of Sitravatinib (MGCD516), a Multi-receptor Tyrosine Kinase Inhibitor, in Advanced Liposarcoma and Other Soft Tissue Sarcomas

Columbia University·interventional·Posted Dec 1, 2016·Updated Jul 18, 2024

In Brief

A Phase 2 clinical trial evaluating MGCD516 for Liposarcoma and Metastatic Liposarcoma. Completed, enrolled 29 participants across 3 sites.

Detailed Summary

The purpose of this study is to evaluate Sitravatinib, an oral small molecular receptor tyrosine kinase inhibitor, for the treatment of advanced liposarcoma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedDec 1, 2016
Enrollment StartNov 1, 2016
Primary CompletionJan 1, 2020
Study CompletionDec 20, 2021
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 9.6 years ago

Interventions

MGCD516drug

Administered at 150 mg orally, daily, in continuous 21 day cycles. An orally available, potent small molecular inhibitor of several related receptor tyrosine kinases.