CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 3,506 enrolled
Drug / intervention
Red Blood Cell Transfusionbiological
Likely dose
Transfusion of packed red blood cell unitsAI-extracted
Key inclusion· 4
  • Age 18 years or older
  • ST-elevation or non-ST-elevation myocardial infarction on admission or during index hospitalization, meeting 3rd Universal Definition criteria
  • Hemoglobin concentration <10 g/dL at time of randomization
  • Physician believes both transfusion strategies are consistent with good medical care
Key exclusion· 8
  • Uncontrolled acute bleeding requiring uncrossed or non-type specific blood at randomization
  • Patient declines blood transfusion
  • Scheduled for cardiac surgery during current admission
  • Receiving only palliative treatment

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02981407
NCT02981407Phase 3Completed

Myocardial Ischemia and Transfusion

Rutgers, The State University of New Jersey·interventional·Posted Dec 5, 2016·Updated May 9, 2024

In Brief

A Phase 3 clinical trial evaluating Red Blood Cell Transfusion for Myocardial Infarction and Anemia. Completed, enrolled 3,506 participants across 133 sites in 6 countries.

Detailed Summary

The purpose of this study is to compare two red blood cell transfusion strategies (liberal and restrictive) for patients who have had an acute myocardial infarction and are anemic.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Brazil, Canada, France, New Zealand, United States

Timeline

Phase 3CompletedFinished
2017201820192020202120222023202420252026
First PostedDec 5, 2016
Enrollment StartApr 25, 2017
Primary CompletionMay 31, 2023
Study CompletionOct 20, 2023
TodayJul 2, 2026
Enrollment to primary: 6.1 yearsPosted 9.6 years ago

Interventions

Red Blood Cell Transfusionbiological

Transfusion of packed red blood cell units