At a glance
ClinicalIndex Comparison Record- ✓Age 18 or older
- ✓Stage I NSCLC, pathologically proven or highly suspicious on imaging
- ✓Primary tumor ≤5 cm on CT
- ✓Karnofsky performance status ≥70
- ✕Previously determined by thoracic surgeon to be medically inoperable
- ✕Pathological confirmation of nodal or distant metastasis
- ✕Prior history of lung cancer (excluding current lesion)
- ✕Prior thoracic surgery or lung/esophageal cancer
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
CSP #2005 - Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy Trial (VALOR)
In Brief
A clinical study evaluating Stereotactic Radiotherapy and Anatomic Pulmonary Resection for Lung Neoplasm. Currently recruiting, targeting 670 participants across 17 sites.
Detailed Summary
Patients with stage I non-small cell lung cancer have been historically treated with surgery whenever they are fit for an operation. However, an alternative treatment known as stereotactic radiotherapy now appears to offer an equally effective alternative. Doctors believe both are good treatments and are therefore conducting this study to determine if one may be possibly better than the other.
Study Details
Timeline
Interventions
Stereotactic radiotherapy uses high doses of ionizing energy to treat cancer cells with image guidance. The treatment is delivered in an outpatient setting, and for purposes of this trial is delivered in 3-5 fractions.
An anatomic pulmonary resection is an oncologic procedure that dissects out an anatomically defined segment of the lung to remove all of the lung tissue around a lung tumor. It requires an operation with general anesthesia, with a short hospital stay. The procedure entails removal of lymph nodes inside the chest that might not be easily accessible without an operation.