CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 2,009 enrolled
Drug / intervention
STRIP intervention +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02986425
NCT02986425N/ACompleted

OPERAM: OPtimising thERapy to Prevent Avoidable Hospital Admissions in the Multimorbid Older People: a Cluster Randomised Controlled Trial

Insel Gruppe AG, University Hospital Bern·interventional·Posted Dec 8, 2016·Updated Aug 25, 2020

In Brief

A clinical study evaluating STRIP intervention and Control for 3 or More Chronic Conditions for 6 Months or Longer and 5 or More Regular Drugs. Completed, enrolled 2,009 participants across 4 sites in 4 countries.

Detailed Summary

The objective of this Randomised Controlled Trial (RCT) is to evaluate whether the Systematic Tool to Reduce Inappropriate Prescribing (STRIP) including STRIP assistant (STRIPA) implemented by an appropriately qualified team will lead to an improvement in clinical and economic outcomes among patients aged 70 years and more with multimorbidity and polypharmacy.

Study Details

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedDec 8, 2016
Enrollment StartDec 1, 2016
Primary CompletionOct 1, 2019
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 9.6 years ago

Interventions

STRIP interventionother

The STRIP intervention consists of 9 steps: 1. structured history taking of medication 2. recording medication and diagnoses in STRIPA 3. structured drug review based on the STRIPA with the integrated Screening Tool of Older Person's Prescriptions (STOPP)/ Screening Tool to Alert Doctors to the Right Treatment (START) criteria 4. communication and discussion of the structured drug review with prescribing physician with possible adaptation of the recommendation 5. shared decision-making with the patient with possible adaptation of the recommendation 6. optional revision based on new accumulating data during hospitalisation (e.g. new diagnoses, adverse drug reactions) 7. generation of general practioner (GP) report 8. delivery of the report to the patient and to the GP (optional additional direct communication) 9. follow-up

Controlother

Standard care in the department where the trial is conducted. To keep the patients and the blinded team members blinded one questionnaire will be conducted by the intervention team in both arms. This is considered a SHAM intervention.